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SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

Abstract Introduction: Aging is accompanied by cardiovascular disorders which is associated with an imbalance of pro- and antioxidant systems, the mitochondrial dysfunction, etc

Biochem Pharmacol 66(6):947-54

In vitro studies demonstrate its role in modulating inflammatory gene expression profiles

Building on these findings, Ottaviani et al

This study is the first of its kind which shows that arsenic can directly bind to Cx43 via its highly conserved cysteine residues causing misfolding of Cx43, which leads to alteration of transportation, localization and oligomerization of Cx43