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ROS, particularly hydroxyl radicals, interact with DNA bases, leading to base modifications, strand breaks, and the formation of oxidative lesions

Glutathione ($25): A powerful antioxidant that aids in detoxification

Pain, prevalent in 3079% of patients, often necessitates analgesics, with chronic pain linked to poor functional status

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Apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway-dependent cytoplasmic translocation of the orphan nuclear receptor NR4A2 is required for oxidative stress-induced necrosis

Additionally, a lower abundance of Bacteroides and Streptococcus in the gut microbiota is a feature of SCZ, and these bacteria are associated with glutamate and GABA metabolism 89