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In the mammalian circadian clock, CRY proteins essentially replace tim and partner with PER proteins to form repressor complexes that drive rhythmic gene expression (Yagita et al., 2002

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Exposure to toxins, whether that is environmental toxins from gasoline or plastic or, you know, whatever industrial activity, or it is exposure to ethanol from all the drinks you are having or it is exposure to cigarette smoke from what you are smoking or what someone else is smoking in the enclosed room with you

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