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If you don't eat animal products, you can change your diet to include vitamin B12-fortified breads and cereals or B12 supplements

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While this methylation reaction was historically considered a relatively minor metabolic pathway for nicotinamide clearance, research over the past decade has revealed that NNMT plays a surprisingly important and previously underappreciated role in cellular energy metabolism, NAD+ homeostasis, adipocyte biology, and whole-body metabolic regulation

Still, we always start with comprehensive testing and a detailed health history to ensure the therapy is right for you

That said, signs or symptoms that you may be low in vitamin B12 include: fatigue pale skin headaches symptoms of depression stomach issues difficulty focusing or concentrating pain or inflammation in the mouth or on the tongue burning or pins and needles feeling in your hands or feet muscle cramps vision changes Learn more: Signs and symptoms of B12 deficiency

By replenishing B12 levels, you can help your skin retain moisture, leading to a softer, smoother appearance