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M.HoltzmanD

Review criteria Published research papers, clinical trials, and literature reviews were selected using different keywords (e.g., NF1, neurofibroma, malignant peripheral nerve sheath tumour, optic glioma) and database sources (e.g., PubMed, Google Scholar, ISI Proceedings, Journal storage [JSTOR] Search, Medline, Scopus, Web of Science, Clinicaltrials.gov)

GPS has been observed to suppress the expression or activity of certain CDKs and cyclins essential for the transition from the G0/G1 phase to the S phase (Li et al., 2019)

A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome

Its complete sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP), with the same Pro-Gly-Pro stabilising motif as Semax

SUb2 recognizes the other (K48-linked) uniquitin molecule and the N-terminal ubiquitin-like domain of ISG15 (refs 74,76 ) (Fig