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There, it binds to ARE (antioxidant response element) sequences [76, 77], initiating the expression of genes encoding detoxification and antioxidant enzymes

In general, the genetic studies on ME/CFS show lots of connections to the immune response and inflammatory cytokines

Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes