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Glutathione also plays a vital role in the formation of white and red blood cells, preventing systemic inflammation and supporting liver functioning

Here's the nuance, though

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Both pathways trigger this vesicle release, but through different intracellular signals

Mitigation strategies include strict sun protection during treatment, using moderate rather than aggressive microneedling depths, incorporating niacinamide which helps prevent PIH, considering patch testing before full-face treatment, and being prepared to pause treatment if significant PIH develops