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furthermore, preeclamptic dams injected with these regenerated extensive placental vascularity ( In a different investigation, it was shown that EXOs miR-139-5p from HUCMSCs-EXOs accelerated trophoblast invasion and migration, activated the ERK/MMP-2 pathway, and blocked trophoblast apoptosis by decreasing protein tyrosine phosphatase expression, all of which improved PE manifestations in rats (Liu et al., 2020b)

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10.1016/j.neuro.2008.03.004 Neurotoxicology

doi: 10.1007/s13181-012-0242-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 92.Pizon AF, Jang DH, Wang HE

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Exposure to p28 increased the level of Pirh2, possibly as a result of significant post-translational increase in p53 and TAp73 in this cell line (Figure 7)