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Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) is increased in DKD mice in association with a C1P-deficient state in podocytes (6264)

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The rate of response was 97.01% (i.e., 195 participants completed the questionnaire, of whom 188 provided blood samples)

In Embodiment 60 of this disclosure are compounds of Formula I, I-a, or I-b, or Embodiments 1-59, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 7 is F, Cl, oxo, OCHF 2 , CH 3 , CN, deuterium, or cyclopropyl

J Cardiovasc Pharmacol 1992;20:157-64

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