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Description

Sameer and his team

In brief, HeLa cells were transfected with VSVG-ts045-KDELR-Myc in the pRose vector for 1 day, and then incubated at 32C for 8 hours to achieve steady-state distribution at the Golgi

KubotaTShindoYTokunoKKomatsuHOgawaHKudoSet al

This approach mirrors dosing strategies used for other peptides with 1216 hour half-lives, though published 5-amino-1mq pharmacokinetic data in humans remains limited