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Advanced non-pharmacological interventions Currently, beyond pharmacological treatments, deep brain stimulation (DBS) has become an effective surgical modality for addressing motor complications in PD

doi: 10.1038/ni.1980 132 JounaiNTakeshitaFKobiyamaKSawanoAMiyawakiAXinKQet al

Ungerstedt U, Arbuthnott GW (1970) Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

Human clinical trial activity is emerging

For example, proteomic studies of breast cancer revealed that overexpression of GLO1 was significantly associated with the grading of breast cancer (150)