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Trends Pharmacol Sci (2012) 33(12):65668.10.1016/j.tips.2012.09.007 65 TewKDTownsendDM

Figure 1A shows the X-ray diffraction pattern of the prepared nanoparticles

This review highlights the currently underexplored role of methyltransferase Set7/9 in the regulation of ROS signaling and oxidative stress response and subsequently raises a question of whether inhibitors of Set7/9 activity can be used to therapeutically alleviate the consequences of ROS imbalance