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These animal ADME findings help drug-development research, but they do not define long-term human safety, immune response, drug interactions, or optimal dosing [10] [16]

This was significantly more than the placebo group, which only lost an average of 2.4% of their body weight

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459 In rat models of T1DM, thalamic ventroposterolateral neurons exhibit hyperexcitability in response to stimuli

Scientists said the data was further encouraging news, with Prof Trudie Lang from the University of Oxford describing it as "a remarkable and very reassuring situation"