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Further, the difference in the accumulation profile was analyzed across a range of physicochemical parameters, including hydrogen bonding numbers, rotatable bonds, molecular weight, topological polar surface area, ClogP, and logS (Fig

And the treatment discontinuation rate due to adverse events rose to approximately 6%, still reasonable but six times higher than cagrilintide monotherapy

After injection : advise the patient about local care, warn about signs of systemic reactions and schedule follow-up labs when risks exist

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