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Expected timeline: Month 1-2: Inflammation management, symptomatic improvement Month 3-6: Potential slowing of degenerative markers, quality of life improvement Month 6-12: Assessment of structural changes, protocol optimization Ongoing: Maintenance protocols as needed, cycling strategies Complementary approaches: Anti-inflammatory nutrition

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The involvement of NF-B and MAPK signaling pathways in IBD is shown in ( Figure 4 )

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doi: 10.1002/pmic.201800311 51 ZouYPalteMJDeikAALiHEatonJKWangWet al

[PubMed ID: 17327744]