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J Clin Endocrinol Metab (2007) 92:15929.10.1210/jc.2006-2084 51 DanilaDCHaidarJNSZhangXKatznelsonLCullerMDKlibanskiA

The muscles in the heart contain high concentrations of copper, and may be negatively affected by either a deficiency or toxicity of the mineral

and O-outcome: an assessment of potential therapeutic strategies (antibacterial and antitumor activity, the ability to modulate immune responses, their role in tissue regeneration processes, and their potential to stimulate stem cell differentiation), and the development of new approaches for future study and their clinical application

As discussed below, the diet-induced overfat condition is also associated with malnutrition, which can impair immunity

doi: 10.3390/ijms14047231 88 ReiterRJTanDXOsunaCGittoE

Upregulation of SLC7A11 increases glutamate output in cells, whereas downregulation of EAAT reduces intracellular glutamate input (Dahlmanns et al., 2023)