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Orthomolecular medicine utilizes the vitamins, minerals, and other nutritional agents that are either naturally occurring in the body or found in foods that build and support the function of healthy cells

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1999 Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells Oncogene 18 : 63806387 Sanchez A, Alvarez AM, Benito M, Fabregat I

Peripheral and central inflammation may be linked through the ability of systemic inflammatory mediators to travel through a leaky BBB, as UPFs have previously been shown to compromise BBB integrity (117)