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Abstract Selenium (Se), an essential trace element, is inserted as selenocysteine into an array of functional proteins and forms the core of various enzymes that play a cardinal role in antioxidant defense mechanisms, in redox regulation, and in thyroid hormone metabolism

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Acknowledgements The authors thank Ganofarm R&D Private Limited, Tanjung Sepat, Selangor Darul Ehsan, Malaysia for providing the mushroom sample

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