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(1998) characterized the compounds as Ang IV receptor agonists and some of them, e.g., 8 with the straight four-carbon chain of the Nle residue at position one, exhibited very high affinity to the binding site (IC50 values 30-fold higher affinity (Ki = 1.7 nM) than Ang IV and improved both selectivity and metabolic stability (Lukaszuk et al., 2008

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The elucidation of antioxidant defense systems in ferroptosis regulation has advanced our integrated understanding of the interplay between iron metabolism and oxidative stress in regulated cell death

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Eur J Neurosci 19(8):20692079 Renna M et al (2013) IGF-1 receptor antagonism inhibits autophagy