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[DOI] [PubMed] [Google Scholar] 275.Jhan JK, Chung YC, Chen GH, et al

4.3.4 Gamma-aminobutyric acid Gamma-aminobutyric acid (GABA), a dual-function neurotransmitter with both excitatory and inhibitory properties in the ENS, regulates gastrointestinal functions via ionotropic (GABA_A/C) and metabotropic (GABA_B) receptors, exhibiting segment-specific and receptor subtype-specific effects: in the stomach, GABA_A receptor activation mediates smooth muscle relaxation through NO release, while GABA_B receptors promote contraction by enhancing cholinergic signaling

These microorganisms have been shown to improve fish health, growth performance, and survival rates, as well as enhance the expression of several immunological factors and reduce the pathogen load to the gut mucus layer ( Oreochromis niloticus ) fed with the probiotic strain of Lactobacillus sp (Hamdan et al., 2016)