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Psychological and biochemical explanations have been suggested ( Reference Eliakim, Abulafia and Sherer 6 )

The effects of thyroid state on beta-adrenergic and serotonergic receptors in rat brain

Disruption of the circadian clock results in loss of rhythmic chaperonemediated autophagy activity and significant changes in the chaperonemediated autophagydependent cellular proteome [118]