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Yamashita A, Takeuchi O

The results imply that even residues not directly involved in the interaction may exhibit changes in their chemical environment if they are adjacent to residues crucial for the interaction or undergo conformational changes upon binding 39,40

Understanding peptide safety helps prevent and manage these situations

Instead of a one-size-fits-all approach, we offer specialized liposomal architectures optimized for specific peptide variants and efficacy targets

Normally GHK-Cu in its raw form is not overly effective orally as this tripeptide doesn't withstand the stomach acid nor the proteolytic enzymes in the stomach beyond at best 10-15% absorption

All authors have read and agreed to the final version of this manuscript