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10.1038/nrm3391 113 PengS.ZhaoD.LiQ.WangM.ZhangS.PangK.et al (2022)

L-methylfolate supports healthy homocysteine levels and endothelial function. IVF treatment : Women taking methylfolate with B12 had better supported fertility wellness compared to folic acid (60% vs 45% clinical pregnancy rate). People who do not tolerate folinic acid (possible MTHFS variantssee below)