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This process underscores the interconnected nature of ecosystems, where fungi act as conduits for essential compounds, enriching the nutritional profile of plants and subsequently contributing to the overall dietary intake of ergothioneine in humans

Limited data suggest vigilance for potential long-term effects like overgrowth, though rare in controlled animal studies

LIST OF ABBREVIATIONS ALS Amyotrophic Lateral Sclerosis BBB Blood-brain Barrier CNS Central Nervous System DATS Diallyl Trisulfide DMC Dimethoxy Curcumin EGCG Epigallocatechin Gallate HT Hydroxytyrosol NO Nitric Oxide OS Oxidative Stress RNS Reactive Nitrogen Species ROS Reactive Oxygen Species RyR Ryanodine Receptors CONSENT FOR PUBLICATION Not applicable