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The lack of clinical trials may be attributed to the relatively recent identification of ferroptosis and the ongoing investigations of its mechanistic links to Exos

Raw reads for individual samples were assessed with the FastQC program ( to check sequence quality and processed with Trimmomatic version 0.36 54 to remove adaptor sequences and bases with low quality scores

Cell death-associated EET formation involves chromatin disassembly and cell membrane lysis, leading to the release of DNA, histones and granule proteins (Ueki et al., 2013)

Casadevall, A., Dadachova, E

Janzen DJ, Allen LJ, MacGregor KB, Bown AW (2001) Cytosolic acidification and gamma-aminobutyric acid synthesis during the oxidative burst in isolated Asparagus sprengeri mesophyll cells