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In differentiated human adipocytes in vitro , GLP-1 can regulate the expression of adipogenesis and lipolytic genes [47]

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Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

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Impaired mitochondrial function due to the downregulation of nuclear-encoded genes involved in oxidative phosphorylation increases ROS production, which in turn phosphorylates the serine residues of insulin receptors and IRSs, thereby resulting in SLCI and a reduction in IR