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The diagnostic criteria for hypertension were an average systolic blood pressure (SBP) 140 mmHg or diastolic blood pressure (DBP) 90 mmHg (measured three times at 5-min intervals), or 24-h SBP 130 mmHg or 24-h DBP 80 mmHg, or a history of hypertension with treatment using antihypertensive medications (12)

The nutritional metabolism has a crucial role in the etiology and developmental complications in type 2 diabetes

These changes disrupt the normal functioning of the lacrimal gland, leading to a reduction in tear production, a key factor in the development of DE symptoms [137]

Angiotensin-converting enzyme levels for sarcoidosis Small fiber neuropathy is common in sarcoidosis, occurring in more than 30% of patients with systemic disease

42 It is absorbed throughout the small intestine, 49 and excess choline transiting to the large bowel is metabolised to methylamines by colonic bacteria

Data availability All datasets generated and/or analyzed during the current study are presented in the article, the accompanying Source Data or Supplementary Information files, or are available from the corresponding author upon reasonable request