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Besides AD, DFO alone or co/treatment with ferrostatin (Fer-1, inhibitor of lipid peroxidation) also improved -synuclein-induced pathology in a PD animal model (Ritchie et al., 2003)

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Thus, MET signaling is implicated not only in neuronal growth and maturation but also in the timing regulation of synaptic plasticity during forebrain glutamatergic circuit development (Ma et al., 2019)