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One possible criticism of this study or that while what we are observing with yeast may not be true, in case of mammalian cells response could be different and one might be experiencing oxidative stress response in the mammalian system, though not the yeast model

Phospholipase C - Manual Phospholipase C (originally called lecithinase and also referred to as -toxin) catalyzes the hydrolysis of the linkage between glycerol and phosphate in lecithin and other phosphatides

It is suggested that Gq protein activation induces PLC/PIP 2 hydrolysis and generates IP 3 and DAG, which stimulate TRPC and increase intracellular Ca 2+ in response to light stimulation (Contreras et al., 2021

A study by Martin-Rincon et al

Chen MH, Chen PC, Lu CH, Chen HL, Chao YP, Li SH, Chen YW, Lin WC (2017) Plasma DNA mediate autonomic dysfunctions and white matter injuries in patients with parkinsons disease

Vasylyev et al., 2023