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AstraZenecas esomeprazole (Nexium) lifecycle illustrates this: after omeprazole generics flooded the market, AstraZeneca launched the S-enantiomer with new method-of-use patents covering specific GERD indications, buying several additional years of premium pricing

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Protocatechuic acid ameliorates high glucose-induced extracellular matrix accumulation in diabetic nephropathy

Most peptides are rapidly degraded by stomach acid and digestive enzymes - BPC-157 survives in conditions that destroy other peptides, which makes biological sense given its origin from gastric juice

Because the 0.9% benzyl alcohol preservative allows repeated withdrawals without re-sterilising the vial, a single 10ml supply can support multiple reconstitution events across a single research project, reducing both cost and vial waste compared to single-use sterile water for injection.

The lack of an antitumour effect from the loss of intracellular GSH suggested that extracellular GSH is instead crucial for tumour growth