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Often split into two injections: 250mcg fasted AM and 250mcg pre-bed

Adiponectin gene expression and adipocyte diameter: a comparison between epicardial and subcutaneous adipose tissue in men

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Subcutaneous administration achieves brain concentrations twice plasma levels (t 1/2 ~10.5 hr) with no toxicity observed at 15 the therapeutic dose in rats

Oral administration significantly reduces lipogenic activity and increases lipolytic activity in adipose tissue, with concurrent increases in fat and glucose oxidation and elevated energy expenditure

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