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For instance, it may affect the activity of enzymes such as hormone-sensitive lipase (HSL), which is one of the key enzymes in the axunge breakdown process and can catalyze the hydrolysis of triglycerides into diglycerol esters and free fatty acids

As a general guideline: 1-7 days at 4C, 1-4 weeks at -20C, and months to years at -80C

& Vecchi, G

The accessory is not requiredthe serum can be applied normally with clean fingertips as a daily leave-in treatment

Without the blood result, I cannot make that call