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To visualize the TfRs, cells were co-stained with AF-labeled antibodies to TfR1

CJC-1295 with DAC Dosing For the long-acting CJC-1295 with DAC variant (completely different from no DAC): Research Dose: 30-60mcg per kilogram of body weight Frequency: Once or twice weekly (due to extended half-life) Example: A 90kg (200lb) person = 2,700-5,400mcg per injection Duration: Ongoing with medical monitoring Source: PubMed Clinical Study - "Subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in GH and IGF-I levels in healthy adults and was safe and relatively well tolerated, particularly at doses of 30 or 60 microg/kg" Important: This is a clinical research dose for CJC-1295 WITH DAC

Saqcena, M

Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b

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E.BellaireB.CatlingA.et al (2014)