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These timepoints were selected to represent distinct stages of iHLO development and maturation: Day 7 signifies the hepatoblast differentiation stage, Day 15 marks the early hepatocyte stage, and Day 30 and Day 45 indicate progressively matured liver organoid stages with increasing liver cell populations and functions

Cells in 6-well plates were labeled with 2 M BODIPY for 30 min, trypsinized, strained, resuspended in FACS buffer, and analyzed by flow cytometry (FITC/Texas Red channels on a BD LSRFortessa TM cell analyzer)

Reconstitution and Handling GHK-Cu is supplied as a lyophilised powder (usually as the copper complex) in research-grade vials

Convenience and ease of use: Managing a chronic condition like rosacea can be challenging, so simplicity is key

Nephrotoxicity of anticancer drugs--an underestimated problem

Their reactivity is based on the 1,3-dicarbonyl chemistry originally demonstrated with dimedone