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Post-hoc analyses revealed that fat mass and percent fat mass were greater in APOE4 males compared to APOE4 females, while there was no sex effect in APOE3 mice

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To identify the specific glucose transporters that play a major role in the glucotonic effect induced by metformin, mRNA levels of multiple glucose transporters were examined using both rat ileum (IEC6) and human colon (Caco-2) cell lines