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Furthermore, high-throughput 16S rRNA sequencing from stool samples identified increased gut inflammation markers, such as elevated levels of Lactonifactor and Alistipes [23]

In fact, an interventional study dating all the way back to 1993 looked at patients with severe, active rheumatoid arthritis

Think of SASP as "biochemical smoke bombs": they disrupt the surrounding tissue, spark chronic inflammation in fat cells, and trigger metabolic chaosinsulin resistance, high blood sugar, and even faster whole-body aging