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Pentoxifylline, an old anti-hypertensive named Trental, has the most recent literature with some scant data supporting its use

PMC 3827408

At the molecular level, chronic AOD9604 administration upregulates 3 adrenergic receptors in fat tissue, reversing obesityrelated suppression of these fatburning receptors [9]

Diabetic painful neuropathy has been shown to be mediated via an inflammatory chemokine pathway (23) and strategies to reduce this inflammation, including gene transfer of soluble TNF receptor, have been shown to alleviate pain (24)