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The liver is one of the hardest-working organs in the body

Regarding hydrophobic bonds, the ligands were bound to the following residues of GPx4: Ile22, Val57, Ala61, Phe78, Ala94, Tyr96, Ile129, Leu130, Ala133, Trp136, Pro155, and Met156 for Ferrostatin

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When the patients were divided into two groups such as the higher and lower groups according to the median value of GPX-3 concentration of 82.8 ng/mL, in Kaplan Meier survival analysis, however, no significant difference in cumulative patients survival rates between patients in the higher and lower groups was observed (Supplementary Figure S2)

Alternative transcription of gpx-4 into Phospholipid-Hydroperoxide glutathione peroxidase variants

3.1 Overview of apoptosis Apoptosis is characterized by distinct cellular changes, including cell shrinkage, chromatin condensation, nuclear fragmentation, and the formation of apoptotic bodies