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This lack of efficacy among smokers is likely due to the difficulties created by cigarette dependence or other barriers to successful cessation, including nicotine withdrawal or cravings, perceived stress relief, or risk of relapse (10, 11)

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Activation of Alpha7 Nicotinic Acetylcholine Receptors Prevents Monosodium Iodoacetate-Induced Osteoarthritis in Rats

Of note, comparisons of rates of CAPS across subsets of PWUC were only interpreted if each subset included at least 15 individuals with CAPS

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