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Despite the slightly less negative midpoint potential of roGFP1-iL compared with roGFP2-iL, the kinetic properties of both probes for reduction by GSH are very similar

In mitochondria, the opening of VDACs plays a key role in mitochondrial dysfunction during ferroptosis, and multiple metabolic enzymes are influenced by ferroptosis

GenBank AA305458 EST176438 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end, mRNA sequence

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Parametric or non-parametric comparisons were used as dictated by data distribution

Investigating the underlying molecular mechanisms, GHK-Cu was found to block critical signaling pathways