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If a vial is missing this critical information, you should not use it

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Sirolimus is an mTOR (mammalian target of rapamycin) inhibitor, mTOR is a protein kinase that is thought to play a role in several key hallmarks of aging including loss of protostasis, deregulated nutrient sensing, cellular senescence, mitochondrial dysfunction, and stem cell exhaustion

The proposed methodology modifies the assignment of those achievement points such that MIPS eligible clinicians performing near the median for a cost measure would be more likely to receive a neutral score consistent with the performance threshold than a negative score, which they would be more likely to receive under the current scoring methodology