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In addition, experimental animal research has shown that sulforaphane may prevent the development of MetS hallmarks such as diabetes, hypertension, and hyperlipidemia (256)

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Simultaneously, calcium overload caused by Na + /H + (NHE) and Na + /Ca 2+ (NCX) exchange mechanisms during myocardial hypoxia and reoxygenation generates substantial ROS, synergistically inducing ferroptosis [142]