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Pros Accurate Detection: Nicotine tests provide specific, measurable evidence of smoking that can confirm or refute suspicions, leading to targeted remediation Policy Enforcement: Clear evidence from tests can help operators enforce non-smoking policies more effectively and fairly by correlating violations with tangible evidence Customer Confidence: Demonstrating the use of rigorous testing procedures can build trust with customers, ensuring them of a smoke-free environment Cons Cost of Testing Kits: Regular use of nicotine testing kits can become costly, especially for large fleets requiring frequent testing Increased Vehicle Downtime: Time-consuming cleaning with test kits can delay vehicle availability for users Labor-Intensive Process: Performing tests on multiple vehicles needs many employees and does not scale well Potential for False Positives/Negatives: While reliable, chemical tests are not infallible and can sometimes produce false results, leading to unnecessary actions or missed detections 5

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Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects