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Edens, and P

The catalytic and regulatory loops of all GS enzymes including Hpy GS are well conserved, resulting in a similar biosynthetic mechanism

Long-term continuous use without breaks may lead to reduced effectiveness

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

They are commonly divided into hydroxybenzoic acids (e.g., gallic, p-hydroxybenzoic acids) and hydroxycinnamic acids (e.g., caffeic, ferulic, p-coumaric acids) (31)