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While many reviews have focused on Mn homeostasis, the aim of this review is to concisely synthesize what we know about its effect primarily on the nervous system with respect to its role in protein misfolding, mitochondrial dysfunction, and consequently, neuroinflammation and neurodegeneration

This process, known as central sensitization , occurs when the nervous system remains in a heightened threat or stress state

Eligibility and prescriptions are based on provider evaluation

Its major compound "Curcumin", acts to restore adequate glutathione levels and enhance glutathione enzyme activity

These by-products can also be rich in bioactive compounds and present beneficial properties [208,209,210]

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