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Ferroptosis is characterized by the iron-dependent accumulation of toxic lipid peroxides that are normally maintained by antioxidants such as GPX4

91 There is a long history of referring to the glia that surround CNS as glial scars or as astrocyte scars, but multiple lines of evidence challenge this usage

While IDH wild-type tumors do not produce 2-HG, they do demonstrate some subtype-specific features that indirectly influence tumor metabolism

Among the various ROS, H 2 O 2 triggers the redox mechanism by targeting the receptor including protein tyrosine kinases, tyrosine phosphatases, and transcription factors via secondary messenger in intercellular signaling

Essential amino acids (EAAs) must be obtained through diet and are directly involved in muscle protein synthesis

215 Recent studies have shown that redox regulates epigenetic modifications, including DNA methylation, histone modification, chromatin remodeling, and non-coding RNA (Fig