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Description

But its clinical efficacy is not ideal and glioma resistance to TMZ is the most important reason for chemotherapy failure

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Endo, Y

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doi: 10.3892/ijmm.2021.4852 30

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Compared to the control group, the total effective rate in the treatment group was significantly higher ( P = .029), as shown in Table 2

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S.PesterevaN

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However, if the UPR fails to resolve the excessive buildup of unfolded proteins, it activates signaling pathways that promote inflammation and apoptosis, potentially leading to neurodegenerative disorders

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