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In contrast, the plasmid pGL4-pCD82(-2121- + 1)-luciferase (long fragment, containing the GR binding motif) exhibit high luciferase activity upon DEX treatment (Fig

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The fact that cysteine S -conjugate -lyase activity is widespread in enteric bacteria and that a major portion of cysteine S -conjugates are excreted into the bile suggests that the gut flora may be important for the incorporation of sulfur into some xenobiotics (Larsen and Stevens, 1986)

Because it avoids classical hormone pathways, it does not cause changes in blood pressure or fluid retention

Based on the pronounced protective effects of Cacna1c knockdown and LTCC blockade, it has to be taken into consideration that, beyond its influence on calcium homeostasis at the plasma membrane, Cacna1c is possibly involved in further regulatory pathways at the level of mitochondria

Some patients may benefit from splenectomy as this is an important site of red cell destruction