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128 , 156169 (2018) S.D

Studies show that ammonia, rather than other glutamine metabolites like glutamate or -ketoglutarate, is responsible for activating SREBP cleavage and promoting lipogenesis (Ya et al., 2002)

For instance, hexokinase-2 (HK2), which is highly expressed in cancer cells, is required for increased ribonucleotide synthesis via the nonoxidative PPP 47

Studies demonstrate that pharmacological lipoxygenase inhibition can prevent ferroptosis

Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism

An example is human retinol binding protein, which has a cavity formed by eight -sheet strands