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Shah MZ, Guan Z-H, Din AU, Ali A, Rehman AU, Jan K, et al

The SOAT1 protein converts excess intracellular cholesterol into cholesterol ester, which is then stored in lipid droplets

The total of four conversions of NAD + to NADH in the joint glutamate synthesis/oxidation process suggested [two in astrocytes during the production of -ketoglutarate and one during glutamate oxidation (Figure 3B), together with one in neurons (Figure 5)] may explain the close to 1:1 ratio between rates of glucose oxidation and of glutamine/glutamate (GABA) cycle flux

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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1

doi: 10.1016/j.sajb.2021.12.023 374 NazRSaqibFAwadallahSWahidMLatifMFIqbalIet al